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Antimicrobial and Antiinflammatory Activities of Extracellular Polysaccharides from Nostoc flagelliforme

GUO Jinying, DU Jie, LI Tonghui, REN Guoyan, WANG Ping, ZHANG Yuxian, LI Zhengjun   

  1. College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, China
  • Online:2015-05-15 Published:2015-05-11

Abstract:

Extracellular polysaccharides from Nostoc flagelliforme in liquid suspension culture with BG-11 medium were
obtained. By measuring the diameter of the inhibition zone using filter paper disc diffusion method, the antimicrobial activity
of the exopolysaccharides against different bacteria and fungi were evaluated, and the anti-inflammatory activity was also
tested by examining their effects on the mouse ear swelling induced by xylene and the swelling of hind paws in mice induced
by carrageenin. The results showed that Nostoc flagelliforme extracellular polysaccharides could inhibit Penicillium and
Monascus to a certain degree, but had no inhibitory activity on Rhizopus. Nostoc flagelliforme extracellular polysaccharides
could effectively alleviate the inflammation of mouse ears and hind paws induced by xylene and carrageenin. Therefore,
Nostoc flagelliforme extracellular polysaccharides have certain antimicrobial and antiinflammatory activities.

Key words: Nostoc flagelliforme, extracellular polysaccharides, antimicrobial activity, antiinflammatory activity

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