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Recent Progress in Molecular Mechanism of Acid Resistance in Escherichia coli

CHEN Zhuozhu, KAN Jianquan, SHI Hui*   

  1. Laboratory of Quality and Safety Risk Assessment for Agro-products on Storage and Preservations (Chongqing),
    Ministry of Agriculture, Chongqing Key Laboratory of Produce Processing and Storage, College of Food Science,
    Southwest University, Chongqing 400715, China
  • Online:2015-11-15 Published:2015-12-03

Abstract:

Some strains of Escherichia coli are resistant to strong acid and can survive in acidic conditions, mainly because
they have a variety of acid resistance mechanisms, including a glucose-repressed system, amino-acid-dependent system,
chaperone proteins and systems for stabilizing membrane charge. Understanding the molecular mechanisms of acid
resistance in E. coli can provide new insight into controlling contamination in the food processing industry, and play a
positive role in clinical prevention and treatment of foodborne pathogens. In this paper, the molecular mechanisms of acid
resistance in E. coli are reviewed.

Key words: Escherichia coli, glucose-repressed, amino-acid-dependent, chaperone proteins, membrane charge, crossprotection

CLC Number: