Abstract:

Chitosan-modified crude liposomes and nano liposomes were studied for changes in average diameter, surface
charge and malondialdehyde content after treatment with accelerated oxidation (heating), UV radiation combined with
free radical inducement and in vitro simulated digestion. The results showed that, after each treatment, the stability of the
chitosan-coated liposomes was significantly higher than bare liposomes. The higher the concentration of chitosan, the
stronger the stability of coated liposomes under environment stress and digestion.

Key words: liposomes, chitosan, digestion, stability