Abstract: In this paper, a gas chromatograph-mass spectrometry (GC-MS) was used to qualitatively and quantitatively analyze the migration of dodecamethylcyclohexasiloxane (D6) from food contact silicone rubber into a liquid food stimulant. Meanwhile, the uncertainty of each variable was also analyzed. The most important factors that affect the results of the experiment were identified. GC-MS analysis indicated that the migration level of D6 was about 125.6 mg/kg from a baking mat made from food contact silicone rubber . We summed up five kinds of uncertainties throughout the experimental process. The highest uncertainty was resulted from the standard curve fitting of D6, which was up to 0.028 5. The combined standard uncertainty was 0.046 5 and the relative expanded uncertainty was 0.093. The amount of D6 analyzed by GC-MS varied in the range of ± 11.68 mg/kg taking the experimental uncertainties into consideration.

Key words: silicone rubber, safety, gas chromatograph-mass spectrometry (GC-MS), uncertainty