(1. School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, China; 2. Golden Health Biotechnology Co. Ltd., Foshan 528225, China; 3. Golden Pomelo Biotechnology Co. Ltd., Meizhou 514021, China;4. School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China)