Abstract: Undenatured type II collagen is a type II collagen that can retain the triple helix structure after extraction, and it has great potential in the prevention and treatment of osteoarthritis and rheumatoid arthritis. Type II collagen is widely present in animal cartilage tissues and is tightly combined with proteoglycans. This article introduces readers to the function and structure of undenatured type II collagen, and reviews the methods for the extraction, and qualitative and quantitative characterization of undenatured type II collagen and the current status of its application in the food industry, with the aim of providing references for further processing and comprehensive utilization of undenatured type II collagen.

Key words: undenatured type II collagen; extraction; function; application