Abstract: 70 male ICR mice were randomly divided into six groups:sedentary control group(A),sedentary+oil of Hipprphae rhamnoides(OHR) group(B),immediately exhaustive exercise in control group(C),immediately exhaustive exercise in OHR supplementation group(D),24h recovery exhaustive exercise in control group(E),24 h recovery exhaustive exercise in OHR supplementation group(F).After 6-week swimming program with gradually increasing intensity,these mice carried out an exhaustive swimming before sacrifice.SOD and MDA in liver,myocardium and brain were assayed.The results indicated.1) SOD showed difference among these groups except between E and F in liver except between A and B,D and F in myocardium,except between A and B ,E and F,A and C in brain. when Comparing with A,C and E, SOD activity in B, D and F increased 7.39%,13.1% and -0.716% respectively in liver 0.612%,4.76% and 26.0% respectively in myocardium,and -1.95%,3.88% and 0.992%.2) The concentration of MDA showed significant difference among above groups except between C and D and E and F in liver and myocardium;-no significant difference among above groups in brain.Comparing with A,C and E,MDA content in B,D and F decreased 25.6%,6.06% and 3.37%,respectively in liver,34.1%,5.05% and 0.285% respectively in myocardium,5.11%,-2.29% and 0.631% respectively in brain.So the conclusion luas:OHR supplementation could increase swimming performance significantly,enhance antioxidative status liver,myocardium and brain.

Key words: ICR mice Oil of Hippophae rhamnoides(OHR) Swimming training SOD MDA