The Dtermination of Lovastatin in Red Yeast Rice by HPLC

Abstract

Abstract: Objective： To establish a HPLC method for determining lovastatin in red yeast rice.Method:Under yellow light,the red yeast rice was extracted with ethyl acetate－ PH3.0 phosporic acid solution(1∶ 1)in shaking bed for 2hrs,at the revolving rate of 150r.p.m. and the temperature at 50℃ . Results:The standard curve was linear in the concentration range of 5～ 100μ g/ml(r=0.9999).The average recovery rate was 95.28％ with RSD=2.8％ .Conclusion:The new and practical method could be used for quality assessment of red yeast rice.It was rapid,sensitive and precise with good reproducibility.

Key words: , Red yeast rice Lovastatin HPLC；

ZHANG Yan-Hong, Hou-Tuan-Zhang, ZHANG Sheng. The Dtermination of Lovastatin in Red Yeast Rice by HPLC[J]. FOOD SCIENCE, 2001, 22(7): 67-69.

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The Dtermination of Lovastatin in Red Yeast Rice by HPLC

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