FOOD SCIENCE ›› 2002, Vol. 23 ›› Issue (5): 118-120.

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The Protective Action of Propolis Extract on Activity of Oxygen Free Radicals to Have Induced Erythrocyte Ghost Injury in Rats

 CAO  Wei, WEI  Ya-Hui, CHEN  Jin-Ping   

  • Online:2002-05-15 Published:2012-02-13

Abstract: Both lipid peroxidation and fluorescence polarization were used to dertimne the protective action of propolis extract on the effect of rat erythrocyte ghost injury induced by oxygen-centred free radicals.The results showed that propolis could significantly inhibit lipid oxidation of rat erythrocyte ghost induced by action oxygen free radicals(peroxy radical and hydroxy radical)with dose-dependent effect.The erythrocyte ghost oxidative damage was induced by hydroxy free radical which could decrease membrance fluidity.But propolis(40μg/ml)could improve the membrance fluidity and inhibit the lipid peroxidation.These results showed that propolis could prevent lipid peroxidation in rat erythrocyte ghost damage induced by oxygen free dadicals.

Key words: Propolis , Active oxygen free radicals , Rat erythrocyte ghost injury , Protective action