Abstract: dipheny1-1,3,5-hexatriene,a kind of fluorescence probe,was used to observe the effects of cole pollen flavonoids on the oxidative damage in rat erythrocyte ghost induced by peroxy radical and hydroxy radical.The results demonstrated that both peroxy radical and hrdroxy radical increased the content of malondialdehyde(MDA),decreased membrance fluidity significantly,and caused lipid peroxidation of rat erythrocyte ghost.But cole pollen flavonoids could decrease the content of MDA remarkably,improve the membrance fluidity of rat erythrocyte membrance fluidity and inhibit the lipid peroxidation in rat erythrocyte membrance .These results suggested that cole pollen was a kind of natural antioxidant and could prevent lipid peroxidation in rat erythrocyte membrance damage induced by peroxy radical and hydroxy radical.

Key words: Cole pollen flavonoids , Peroxy radical , Hydroxy radical , Erythrocyte membrance fluidity