Change of Chemical Indexes in Mice’s Blood and Liver in Continuous Administration of MT during 51 Days

Abstract

Abstract: The objects were Kunming mice (♂). The model was set up by continuous administration of MT during 51 days. The indexes included the content of Hemoglobin(Hb) and Malondialdehyde(MDA), the activity of Glutamic-pyruvic Transaminase in serum(SGPT), Glutamin-oxalaceticTransaminase(SGOT) and Superoxide Dismutase(SOD) and Total anti -oxidant Capability(T-AOC). The results showed that continuous administration of MT did not significantly affect Hb content, the activity of SOD in liver and SGOT(P>0.05).The activity of SGPT and the content of MDA in liver and serum significantly decreased(P<0.01). But total anti-oxidation capability(T-AOC)significantly rose(P<0.05). Experimental results suggested that MT being strong in anti-oxidation capability could significantly assist anti-oxidation system of the body.

Key words: Melatonin(MT) , Blood , Liver , Chemical indexes

ZHANG Quan-Jiang, LI Qiu-Xia, XIONG Zheng-Ying. Change of Chemical Indexes in Mice’s Blood and Liver in Continuous Administration of MT during 51 Days[J]. FOOD SCIENCE, 2002, 23(9): 126-129.

[1]	YANG Chenglin, HUANG Chao, LIU Juan, HUANG Weimei, YUAN Zhihang, YI Jin’e, LIANG Zeng’enni, WU Jing. Protective Effect of Betulinic Acid on Liver Injury Induced by T-2 Toxin in Mice [J]. FOOD SCIENCE, 2021, 42(9): 107-114.
[2]	REN Shuang, DONG Wenxia, LIU Jinfang, MAO Like, GAO Yanxiang, YUAN Fang. Progress in Food Delivery Systems Used for Curcumin Encapsulation [J]. FOOD SCIENCE, 2021, 42(9): 264-274.
[3]	YANG Zhongmin, SHEN Yihong, HUANG Xianzhi, WANG Zuwen, DING Xiaowen. Improvement Effect of Mulberry Leaf Alkaloids on Abnormal Glucose and Lipid Metabolism and Liver Injury Induced by Oxidative Stress in Mice [J]. FOOD SCIENCE, 2021, 42(7): 156-161.
[4]	WANG Caixia, BAI Chan, XIONG Guangquan, WANG Juguang, LI Ning, ZU Xiaoyan, LI Hailan, LIAO Tao. Effect of Eugenol Anesthesia on Waterless Live Transportation of Micropterus salmoides [J]. FOOD SCIENCE, 2021, 42(5): 228-236.
[5]	ZHOU Xueyan, CHEN Yu, LIN Ke, ZHANG Dandan, GE Zhengkai, SU Congyan, WANG Bin, SHI Xuewei. Dynamic Changes in the Physicochemical Properties and the Volatile Flavor Compounds in ‘Merlot’ and ‘Vidal’ Icewines during Storage [J]. FOOD SCIENCE, 2021, 42(2): 200-211.
[6]	ZHANG Mingzhu, WU Xuefeng, MU Dongdong, XU Boyang, SUN Wei, JIANG Junshu, YAN Xiaoming, ZHENG Zhi, JIANG Shaotong, LI Xingjiang. High Throughput Sequencing-based Analysis of Prokaryotic Community Structure in Chinese Liquor Fermentation Pit Muds and Its Correlation with Physicochemical Indexes [J]. FOOD SCIENCE, 2021, 42(18): 111-118.
[7]	LI Xidong, SUN Shaoxia, LIANG Yanan, SHI Tala, MI Wei. Hawthorn Proanthocyanidins and Vitamin C Attenuate Liver Oxidative Stress in Insulin Resistance Rats through the Wnt/β-catenin Signaling Pathway [J]. FOOD SCIENCE, 2021, 42(17): 186-192.
[8]	DONG Xiaoli, XIAO Mengchao, YANG Jing, HUANG Jichao, HUANG Suhong, HUANG Ming. Effect of Pre-slaughter Shackling on Gel Properties of Duck Blood [J]. FOOD SCIENCE, 2021, 42(17): 69-75.
[9]	LI Fangfang, ZHANG Ruimeng, CONG He, SHEN Minghua. Protective Effects of Fibrinolytic Enzyme from Lyophyllum ulmarium on Alcohol-Induced Liver Injury in Rats [J]. FOOD SCIENCE, 2021, 42(17): 121-126.
[10]	JIANG Yunjia, LIU Jinyan, XU Saijun, WANG Yang, ZHANG Bin, CHENG Zhong, XU Yang, XIE Yong. The Freshener Inosine 5’-Monophosphate Disodium Aggravates Lipid Metabolic Disorder in Elderly db/db Mice [J]. FOOD SCIENCE, 2021, 42(15): 150-158.
[11]	JIANG Yang, ZHANG Cuiying, LI Yu, XIAO Dongguang. Effect of Flavor Substances in Alcoholic Beverages on Ethanol Metabolism in Human Body: A Review [J]. FOOD SCIENCE, 2021, 42(15): 242-250.
[12]	GE Sitong, JIA Rui, LIU Huimin, ZHENG Mingzhu, CAI Dan, LIU Jingsheng. Progress in Preparation and Application of Zein-Based Nanoparticles [J]. FOOD SCIENCE, 2021, 42(15): 285-292.
[13]	HOU Xinyao, DENG Ziyu, LIANG Hongshan, LI Bin. New Plant-based Carrier for Efficient Delivery and Protection of Lactase [J]. FOOD SCIENCE, 2021, 42(14): 137-143.
[14]	ZHOU Sainan, ZHANG Qing, WANG Fahe, WANG Xiaomei, LI Zhaojie, XUE Changhu, TANG Qingjuan. Optimization by Response Surface Methodology of the Formulation of Seaweeds, Fruits and Vegetables Extracts to Assist in Reducing Blood Glucose and Lipid Levels [J]. FOOD SCIENCE, 2021, 42(13): 57-63.
[15]	WANG Zhi, LIU Haotian, LIU Qian, CHEN Qian, KONG Baohua. A Literature Review of the Application of Maillard Reaction and Its Products in the Delivery of Bioactive Substances [J]. FOOD SCIENCE, 2021, 42(11): 324-331.

Change of Chemical Indexes in Mice’s Blood and Liver in Continuous Administration of MT during 51 Days

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments