Abstract: Objective: To study the effect of trehalose drinks on heat endurance of mice, so as to provide basis for developing a new heat endurance functional beverage. Methods: Using mouse which were fed by different drinks(water, sucrose water and trehalose water) respectively as testing animals which were exposed to 30℃ habitat. The surviving time upon heat exposure and the swimming time were examined and the physiologic and biochemical changes such as body weight, potassium concentration, blood sugar, hemoglobin were compared before and after heat exposure. Results:Trehalose could significantly improve the surviving time upon heat exposure, effectively sustain the hemoglobin level, and keep the potassium concentration in blood serum to protect cells from damage. Likewisly it could increase the blood sugar level and reserve energy. Conclusion: Trehalose could improve the heat endurance of the animal. So trehalose could be a good ingredient in heat sndurance drink.

Key words: trehalose, heat tolerance, animal test