FOOD SCIENCE ›› 2005, Vol. 26 ›› Issue (5): 232-237.

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Study on Preparation of Yolk Antibody Specific Against Helicobacter pylori and It’s of Efficacy Evaluation

 NIE  Zuo-Ming, YANG  Yan-Jun, XU  Rong-Rong, SHENG  Jian-Jun   

  1. School of Food Science and Technology,Southern Yangtze University
  • Online:2005-05-15 Published:2011-09-19

Abstract: In this paper, highly purified immunoglobulin Y against Helicobacter pylori (IgY-HP) was prepared from the egg yolk while immunized with compound antigen of supernatant from HP pulverized by ultrasonic wave while urease was purified form HP.ELISA test indicated that the efficacy for IgY-Hp was 32 times higher than that for IgY in egg yolk from nonimmunized hens. It could be applied to healthcare and to the antibacterial immune treatment for gastric disease associated with HP.

Key words: yolk antibody, Helicobacter pylori, ELISA, titer