Abstract: The mice experiments showed serum lipid-lowering and antioxidative action of the Pentosan isolated from beer`s spent grains. Compared with the hyperlipidemic group, Pentosan isolated from beer,s spent grains could significantly lower the cholesterol levels of mice, including the serum TC, TG, LDL-C and arteriosclerosis index(AI). It could also lower the liver weight, TC and TG. Pentosan isolated from beer’s spent grains also improved SOD activity, reduced MDA content in mice and enhanced GSH-Px activity in blood.

Key words: beer’s spent grains, pentosan, serum lipid-lowering, antioxidative action