Abstract: This articles studied the extraction of flavonoids with the technology of microwave. The effects of average microwave output power, concentrations, diffent solvents and microwave irradiation time on the extraction yield were investigated. The parameters of extraction process were optimized through orthogonal test and average microwave output power was 200W, alcohol concentration was 50%, solid/liquid rate 1:30 and microwave irradiation time was 10min. The orthogonal test result indicated that, the primary factor which influence the result of experiment is the ethyl alcohol density, next is the time of extraction, the material-fluid rate, the microwave output power. The best extraction condition is A2B3C2D3, namely the ethyl alcohol density 50%, extract time 25min, the material-fluid rate 1:30, microwave output power 400W. Under this condition the total content of flavonoids is 0.7672%.

Key words: eucommia, flavonoids, extraction with micro-wave method