Soluble Pressure Estimation and Solubility Determination of Ligustilide from Angelica sinensis Oil with Supercritical CO2 Fluid

Abstract

Abstract: The solubility parameters and soluble pressure of ligustilide (the most important constituent of Angelica sinensis oil) in supercritical CO2 (SC-CO2) extraction was estimated theoretically from the point of molecular structure. This showed that extracting ligustilide from Angelica sinensis by SC-CO2 is feasible, and the extracting temperature 40℃ is better than 50℃. The solubility of Angelica sinensis oil in SC-CO2 was determined by the apparatus with a binary phase equilibrium measurement on high-pressure. The results verify the above estimation. The results also showed that the solubility of ligustilide gets better by cooperating with other components of Angelica sinensis.

Key words: , Angelica sinensis oil； ligustilide； supercritical CO2 (SC-CO2)； solubility parameter； soluble pressure； solubilityd etermination；

HU Chang-ying1,DING Xiao-lin2. Soluble Pressure Estimation and Solubility Determination of Ligustilide from Angelica sinensis Oil with Supercritical CO2 Fluid[J]. FOOD SCIENCE, 2006, 27(12): 238-241.

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Soluble Pressure Estimation and Solubility Determination of Ligustilide from Angelica sinensis Oil with Supercritical CO2 Fluid

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