Abstract: The food safety of transgenic cottonseed and their effects on the antioxidant system of rat were examined. There was no mortality in the study and all animals appeared healthy. The results showed that there are no significant differences in weight gain and feed intake, blood biochemical indices and organs weights between rats consuming transgenic cottonseed and conventional cottonseed diet as control. All rats appear normal in anatomy and histopathology. Similarly, there are no significant differences in antioxidant enzyme activity among groups. The results of numerous analytical measurement demonstrated that the transgenic cottonseed is nutritionally equivalent to the conventional one.

Key words:  , transgenic； cottonseed； food safety； antioxidant system；