FOOD SCIENCE ›› 2006, Vol. 27 ›› Issue (7): 124-128.

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Separation of Antihypertensive Peptides Derived from Yak Milk Casein with Ultra-filtration Technology

 JIANG  Jing-Li, REN  Fa-Zheng, CAI  Hua-Wei   

  1. Key Laboratory of Functional Dairy, Ministry of Education and Municipal Government of Beijing, College of Food Science and Nutritional Engineering, China Agricultrual University, Beijing 100083, China
  • Online:2006-07-15 Published:2011-09-29

Abstract: Antihypertensive peptide derived from yak milk casein was separated by ultra-filtration technology. The effects of pressure, temperature and concentrations of peptides on ultra-filtration permeate flux were investigated. The results showed that the optimum conditions are: 5% peptides, pressure 0.15MPa and temperature 45℃. The relative molecular mass of permeates was investigated by high performance size exclusion chromatography. The results showed that the peptides mixtures can be effectively separated by ultra-filtration. The permeate fractions show higher ACE inhibitory activity than original peptide mixtures.

Key words:  , ultra-filtration; antihypertensive peptides; casein;