Screeningα-Glucosidase Inhibitors from Coruns officinalis(I)

Abstract

Abstract: In this experiment the crude eq-extracts and the components of polysaccharides, tannins, saponins and organic acids were obtained from Cornus officinalis by extraction, isolation and partial purification with yields respectively 9.60%, 2.00%, 2.40%, 0.75%, 4.10%. The results of enzymatic kinetics assays showed that all of the components have inhibitory activities against α-glucosidase except organic acids. Saponins and tannins showed better inhibition effect than double concentration of Glucobay. The experiment confirmed that Cornus officinalis is a good source of α-glucosidase inhibitors and Cornus officinaliss saponins and tannins may become promising candidates for blood sugar reducing function factors.

Key words: , Cornus officinalis； &alpha, -glucosidase inhibitor； saponin； tannin； blood sugar；

MA Qing-Yi, CHEN Li-Hua, YANG Hai-Yan, WANG Qing-Ling. Screeningα-Glucosidase Inhibitors from Coruns officinalis(I)[J]. FOOD SCIENCE, 2007, 28(1): 167-170.

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Screeningα-Glucosidase Inhibitors from Coruns officinalis(I)

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