FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (2): 369-372.

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Review on Nisin Separation Technology from Fermentation Broth

 JI  Yu-Qiang, WU  Zhao-Liang, GUO  Ya-Nan, YU  Guang-He   

  1. 1.Department of Bioengineering, Hebei University of Technology, Tianjin 300130, China; 2.Kangyi Co. Ltd., of Biological Technique, Tianjin 301801, China
  • Online:2007-02-15 Published:2011-12-31

Abstract: Nisin is a bacteriocin produced by Lactococcus. It is widely used as a safe and natural food preservative in food industry. At present, there are a lot of purification and separation methods about nisin in the literature, but whether they are suitable for industrialization needs to be further studied. On the basis of reviewing the present technology for extraction and purification of nisin after fermentation, this paper analysed the difficulties for industrialization of these methods, and envisaged the future development.

Key words: nisin, separation, development