Abstract: Recent research developments ofβ-glucans biosynthesis in S.cerevisiae were detailedly reviewed in this paper.The biosynthesis of solubleβ-glucans resulted from the activity ofβ-glucans synthase and the sugar donor was uridine 5′- diphosphoglucose.The chitin synthascⅢwas capable of incorporating solubleβ-glucans and chitin viaβ-1,4 orβ-1,2 linkages, to changeβ-glucans from soluble to insoluble.Moreover,some current developments of related gene aboutβ-glucans synthase were summarized here.A pair of highly homologous proteins Fks lp and Fks 2p encoded by FKS1 and FKS2 genes,arc necessary inβ-glucans biosynthesis.The GTP-binding protein Rh1p is required for regulation ofβ-1,3-glucans biosynthesis.Many genes which contain KRES,KRE6,CWH4p,ROT2 and SKN1,arc known to affect the levels ofβ-1,6-glucans,but their role of the synthesis remains unknown.In the end,the future research direction and prospect ofβ-glucan’s biosynthesis were discussed.

Key words: &beta, -glucan； Saccharomyces.cerevisiae； biosynthesis； gene；