FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (6): 113-115.

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Selection of Entrainers in Supercritical CO2 Extraction and Crystallization of Andrographolide

 ZHANG  Wen-Cheng, XIE  Hui-Ming   

  1. Engineering Research Center of Bio-process of Ministry of Education, Hefei University of Technology, Hefei 230009, China
  • Online:2007-06-15 Published:2011-12-31

Abstract: With the new technique of supercritical carbon dioxide extraction and crystallization, Andrographolide intermediate was used to investigate the effects of ethanol, acetone and ethyl acetate on the crystallization ratio, purity and crystal configuration on Andrographolide extraction and crystallization. The purity of Andrographolide cooperated with ethyl acetate is the best, the crystallization ratio of Andrographolide cooperated with ethanol, the morphology on Andrographolide cooperated with acetone is the best.

Key words: supercritical CO2, extraction and crystallization, Andrographolide, entrainer