Variation of Composition of Curcuminoids in Rat Body

Abstract

Abstract: Curcuminoids mainly include three homologues:curcumin,demethoxy curcumin and bisdemethoxy curcumin.Objective:This study aims at the exploration of variation of the composition of curcuminoidsin rat body.Methods:Male SD rat was orally administrated with an extract from Curcuma Longa L root.Serum and liver were collected after 2 hour.Feces were collected for 24 hours.Their curcuminoid composition(CC)was assessed by C30-HPLC-PDA.Results:The CC from feces was similar to that from the root extract while curcumin ratio from homogenized liver tissue and serum was significantly higher.Conclusion:An increased curcumin ratio took place in serum.Curcumin was major fraction to access rat body.

Key words: curcuminoids, absorption

WANG Zheng, HUI Bo-Di, PEI Ling-Peng, ZHANG Jing. Variation of Composition of Curcuminoids in Rat Body[J]. FOOD SCIENCE, 2007, 28(9): 542-545.

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Variation of Composition of Curcuminoids in Rat Body

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