Effect of Nostoc sphaeroids Kutz Polysaccharides on Tumor Inhibition and Immunity of Mice in vivo

Abstract

Abstract: The bearing-S180 female mice were injected 50, 100, 200 mg/kg bw·d Nostoc sphaeroids Kutz polysaccharides for 10d, the contrast were injected Cy20 mg/kg bw·d. The tumor index, thymus index, the spleen lymphocyte transformation, the NK cell activity and delayed-type hypersensitivity(DTH), anti-oxidative were determined, in order to inquire into the tumor inhibition and immunity effect of the Nostoc sphaeroids Kutz polysaccharides. Results showed that the Nostoc sphaeroids Kutz polysaccharides can remarkable inhibit the tumor that is related to the dose, the tumor inhibition rate of 50, 100, 200 mg/kg polysaccharides were 29.91%, 38.24%, 64.08%, while it can restrain the cellular immunity which is descended by tumor, but it had effect to mice anti-oxidative.

Key words: Nostoc sphaeroids Kutz, polysaccharides, anti-tumor, immunity, anti-oxidative

MO Kai-Ju, XIE Bi-Jun, GONG Chen-Rui. Effect of Nostoc sphaeroids Kutz Polysaccharides on Tumor Inhibition and Immunity of Mice in vivo[J]. FOOD SCIENCE, 2008, 29(4): 392-396.

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Effect of Nostoc sphaeroids Kutz Polysaccharides on Tumor Inhibition and Immunity of Mice in vivo

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