Effects of Ultrafine Grape Seed Powder on Levels of NO,ET-1 and C-reactive Protein in Plasma of Hyperlipemia Golden Hamsters

Abstract

Abstract: To study the protective effect and mechanism of ultrafine grape seed powder on risk of hyperlipidemia, this experiment was conducted on 100 golden hamsters, which were divided into five groups, each of which contained 20 hamsters: control group, hyperlipidemia group, grape seed low dose group, middle dose group and high dose group. After completion of the trial, the plasma NO, ET-1 and C-reactive protein level were determined in golden hamsters. The results showed ultrafine grape seed powder increases the levels of NO of hyperlipidemia hamsters, and it also significantly decreases the contents of ET-1 and CRP of hyperlipidemia hamsters. Ultrafine grape seed powder can improve the blood vessel function and protect body from atherosclerosis occurrence.

Key words: ultrafine grape seed powder, NO, ET-1, C-reactive protein

GUO Jin-Ying, LI Song-Biao, LIU Kai-Yong, HOU Yu-Ze, CUI Guo-Ting. Effects of Ultrafine Grape Seed Powder on Levels of NO,ET-1 and C-reactive Protein in Plasma of Hyperlipemia Golden Hamsters[J]. FOOD SCIENCE, 2008, 29(9): 598-600.

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Effects of Ultrafine Grape Seed Powder on Levels of NO,ET-1 and C-reactive Protein in Plasma of Hyperlipemia Golden Hamsters

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