FOOD SCIENCE ›› 2013, Vol. 34 ›› Issue (4): 83-87.

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Synthesis of L-Menthyl β-D-Lactoside

  

  • Received:2011-11-21 Revised:2012-12-25 Online:2013-02-25 Published:2013-01-29
  • Contact: Langqiu Chen E-mail:chengood2003@263.net

Abstract: In order to improve the thermostability and water solubility for L-menthol, its molecular structure was modified as a glycosidation derivative. With L-menthol and α-lactose as raw materials, a target compound L-menthyl β-D-Lactoside (4) was synthesized by three-step of acetylation, coupling, and deprotection, the total yield was 42.3%. The intermediate product and target compound were analyzed by melting point, optical rotation, NMR and MS technology. The results have showed that the compound 4 has desirable thermostability and excellent water solubility.

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