Abstract: Technology trends in sample pretreatment, a crucial step in the analysis of complex samples, are of great significance to the development of analytical chemistry. Magnetic solid phase extraction (MSPE) is a novel sample pretreatment technique using magnetic or magnetizable materials as adsorbents. Thanks to its advantages including easy operation, short extraction time, strong anti-interference ability and good biocompatibility, MSPE represents one of the most promising approaches in the field of sample pretreatment. In recent years, with the rapid development of various adsorbent preparation techniques, novel magnetic nanomaterials-based MSPE is widely used for the isolation and enrichment of a variety of compounds in foods. In this review, we summarize the up-to-date advances in the application of MSPE based on graphene/graphene oxide (G/GO), carbon nanotube (CNT), metal organic framework materials (MOFs), covalent organic framework materials (COFs), molecularly imprinted polymers (MIPs), nanocomposite materials or functional polymer materials in food safety detection, and we discuss future development prospects in this field.

Key words: sample pretreatment; novel magnetic nanomaterials; magnetic solid phase extraction; food safety