Abstract: Aquatic product safety incidents have occurred frequently because of serious pollution in the farming environment, use of illicit veterinary drugs during the farming process, and the natural occurrence of pathogenic bacteria in aquatic products. However, due to the low content of target analytes, the complexity of aquatic product matrices, and the interaction between target analytes and food components, it is very difficult to separate and purify residual pollutants from aquatic products, so there is an urgent need for accurate and precise methods with a low limit of detection for the safety detection of aquatic products. Metal-organic frameworks (MOFs) are porous crystalline materials with large specific surface area, good thermal stability, and adjustable surface modification. MOFs have been successfully applied to the safety testing of aquatic products owing to the excellent adsorption properties. This article summarizes the major structure of MOFs, discusses the adsorption mechanisms of MOFs, and reviews the applications of MOFs in the safety detection of residual pollutants (fishery drugs, heavy metals, and organic pollutants) in aquatic products, in order to provide a reference for researchers engaged in the safety detection of aquatic products.

Key words: aquatic products; metal-organic frameworks; adsorbent; safety detection; pollutants