FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (6 ): 80-84.doi: 10.7506/spkx1002-6630-201106018

• Processing Technology • Previous Articles     Next Articles

Optimizzation of Ultrasound-assisted Extraction of Ursolic Acid from Plantago asiatica L. by Response Surface Methodology

KONG Tao,FAN Jie-ping*,HU Xiao-fang,CAO Jing,ZHANG Lu,TONG Sheng   

  1. School of Environmental and Chemical Engineering, Nanchang University, Nanchang 330031, China
  • Received:2010-06-07 Revised:2011-01-25 Online:2011-03-25 Published:2011-03-03
  • Contact: FAN Jie-ping* E-mail:jasperfan@163.com

Abstract: Objective: To optimize the ultrasound-assisted extraction of ursolic acid from Plantago asiatica L.. Methods: On the basis of single-factor experiments, response surface methodology (RSM) was used to explore the optimal conditions for extracting ursolic acid from Plantago asiatica L. following regression analysis of the relationship between extraction parameters and extraction rate of ursolic acid. Results: The optimal extraction conditions were extraction temperature of 75 ℃, ethanol concentration of 90%, ultrasound power of 480 W, liquid/material ratio of 5:1, and extraction time of 25 min. Under the optimal extraction conditions, the extraction rate of ursolic acid was 0.144%. Conclusion: The optimal extraction conditions are reasonable and effective.

Key words: response surface methodology (RSM), ultrasound-assisted extraction, Plantago asiatica L., ursolic acid

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