Effects of AMPK Activity on Glycolysis in Postmortem Lamb Muscle

doi:10.7506/spkx1002-6630-200919029

Abstract

Abstract:

Glycolysis in postmortem lamb muscle was investigated through AMP-activated protein kinase (AMPK) activity modulation using AMPK activators and inhibitors, which could be used to explore physiological mechanisms of postmortem lamb muscle. Results revealed that AMPK activity in postmortem lamb muscle exhibited a significant increase (P < 0.05) and decrease (P < 0.05) using its activators and inhibitors, respectively. The enhanced AMPK activity promoted the declining rate of glycogen content (P > 0.05) and pH (P < 0.05), increased the accumulation of lactate (P < 0.05), hexokinase activity (P < 0.05) and lactate dehydrogenase activity (P < 0.05) in postmortem lamb muscle; in contrast, opposite results were observed under the condition with reduced AMPK activity. Therefore, elevated AMPK activity can promote glycolysis and attenuated AMPK activity can alleviate glycolysis in postmortem lamb muscle.

Key words: AMPK, glycolysis, postmortem lamb muscle, physiological mechanism

CLC Number:

TS201.2

LI Ze，MA Xia，JU Ning，JIN Ye*. Effects of AMPK Activity on Glycolysis in Postmortem Lamb Muscle[J]. FOOD SCIENCE, 2009, 30(19 ): 131-133 https://doi.org/10.7506/spkx1002-6630-200919029

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Effects of AMPK Activity on Glycolysis in Postmortem Lamb Muscle

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