Abstract:  Objective: To study the health functionality of a new yoghourt fermented with haw (or medlar) and Lycium Chinese (SG yoghourt) for reducing blood lipids and immunologic regulation in rat and mouse. Method: The animal model groups of pathology, SG yoghourt, and ordinary yoghourt were assayed respectively. The blood lipids (TC, TG, LDL-C, HDL-C), phagocytose of macrophage, exponents of thymus and spleen, and hemolysin, in animals of vary groups, were assayed and the related effects were observed. Result: There are obviously reduction in blood lipids and regulation of immunology comparing the SG yoghourt group with the pathology group or ordinary yoghourt group (p≤0.05～0.001). Conclusion: SG yoghourt shows the fine function of reducing blood lipids and promoting immunological regulation. The new SG yoghourt has a broad exploiting prospect as a healthful food.

Key words: haw, Lycium Chineses, yoghourt, blood lipid, immune, heart food