Abstract: Some works were carried out about the effects of nine Kinds of Chinese Traditional Medicines on biomass and crude exopolysaccharide of Coprinus comatus in submerged fermentation. The result showed: all medicines, except Astrgalus menbranaceus and Polygonatum odoratum, could improve the fermentation of Coprinus comatus and stimulate the secretion of crude exopolysaccharide in a certain dosage. It could be concluded, by adding medicines in different dosages, that when the optimum dosages of Momordica charantia L., Gynostemma pentaphyllum, Lily, Buckwheat, Radix Salviae miltiorrhizae and Amorphaphallus konjak were respec- tively 0.5%, and the biomass and crude exopolysaccharide could reach the maximum when Ginseng was added at 1.5%.

Key words: Chinese traditiond medieine, Coprinus comatus, fementation, exopolysaacharide