FOOD SCIENCE ›› 2007, Vol. 28 ›› Issue (5): 59-62.

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Effects of Candida utilis Extract Compositions on Glutathione Seperation Efficiency of D001 Cation Ion Exchange Resin Columns

 WANG  Miao, SU  Xiao-Jin   

  1. Key Laboratory of Food Science and Safety,Ministry of Education,School of Food Science and Technology,Southern Yangtze University,Wuxi 214036,China
  • Online:2007-05-15 Published:2011-12-31

Abstract: In this paper,the effects of the Candida utilis WSH 02-08 extract compositions on the glutathione(GSH)adsorption efficiency of D001 cation ion exchange resin columns were studied.The results showed that the big molecular weight polypeptides obviously affects the adsorption efficiency of D001 cation ion exchange resin for GSH.By ultrafiltraion treatment of the extract with respect to a suitable extract method,the content of the big molecular weight polypeptides in sample decreases largely,down to MW<2000 and MW<4000 respectively,whereas the adsorption efficiency of D001 cation ion exchange resin for GSH increases obviously from about 40% to above 70%.

Key words: glutathione, ion exchange, ultrafiltraion