Abstract

Abstract: The mice were administered the various doses of Total Saponins of Panax Ginseng(TSPG) for 7 days and exposedto the normobaric hypoxia. The results showed that TSPG significantly prolonged the survival time in mice. The meansurvival time of the mice with the optimum dose 25mg/kg.d was (35.00±3.88)min. It was longer than the control groupby 35.7%. TSPG could raise the contents of hemoglobin(Hb) in the plasma of the mice, decrease the contents of lactic acidin the brain, heart, liver and improve the activity of lactate dehydrogenase in these tissue.

Key words: Total saponins of panax ginseng , Hypoxia , Hemoglobin , Lactate dehydrogenase

WANG Bin, ZHANG Sheng-Hua, LI Xiao-Li, SU Xi-Sheng, XIE Shou-He. [J]. FOOD SCIENCE, 2002, 23(8): 270-272.

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