FOOD SCIENCE ›› 2002, Vol. 23 ›› Issue (7): 45-47.

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Using Blood Loss Anemia Rat Model for Evaluating EPO Factor Containing Food

 WEN  Jing, ZHAO  Jian, ZHU  Ye, SHEN  Lin, JIN  Zong-Lian   

  • Online:2002-07-15 Published:2011-12-31

Abstract: Objective:Anexperimental method f or evaluating the erythropoietin(EPO)factor containing food was es-tablished.Methods:Through a low ir on containing food and vein nomospasia a blood loss anemia rat model was se t up.The effect of the EPOfactor conta ining food was identified by inspection of the number of red cells and cont ent of hemoglobin,the feasibility of the m ethodwas testedby inspectionofthe number ofredcells andcontentofhem oglobin,thefeasibilityofthemethodwastestedbyexaminingtheeffectofanoraladministrationofthehumanEPOgene expression productinsilkwormchrysalises.Re sults:Usingthebloodloss anemiamo del,throughthenumberofredcellsandcontent ofhemoglobininspection,the effectof trans -EPO -gene product gave a go od effect ofpromoting the productio n of red cells and expediting the synthesis of hemoglobin.Conclusion:The intro duced methods can be used for evaluating the EPOfactor containing foods.

Key words: Erythropoietin , Evaluating method for the functional food , Number of redcells , Hemoglobin