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Progress in Detection of Food Allergens Based on Liquid Chromatography Coupled with Mass Spectrometry

XIONG Li-ji, TONG Ping, XIAO Na, CHEN Hong-bing   

  1. 1. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China;
    2. School of Environment and Chemical Engineering, Nanchang University, Nanchang 330047, China;
    3. Sino-German Joint Research Institute, Nanchang University, Nanchang 330047, China
  • Online:2014-11-15 Published:2014-11-06

Abstract:

Food allergy is currently an important problem in food safety, and the detection of food allergens is of great
significance for protecting allergic consumers. The detection of trace allergenic proteins in a complex food matrix mainly
relies on a reliable analysis method. Liquid chromatography-mass spectrometry (LC-MS) with the advantages of high
throughput, high resolution and high automation is widely used to explore food allergen proteins. This article reviews the
application of LC-MS for detecting allergens in a single or complicated food matrix, and suggests ways to improve the
accuracy of LC-MS. However, further studies are necessary for the detection of allergens in food matrices by LC-MS.

Key words: liquid chromatography-mass spectrometry (LC-MS), food allergen, detection

CLC Number: