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Progress in Quantitative Structure-Activity Relationships Research of Antimicrobial Peptides

LU Yongzhong, KANG Daole   

  1. College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
  • Online:2015-08-15 Published:2015-08-17

Abstract:

Antimicrobial peptides have potential applications in many fields, such as medicine, food, agriculture,
and aquiculture. Quantitative structure-activity relationships (QSAR) research will be helpful for the optimization of
antimicrobial peptides. Herein, the recent progress in molecular description and modeling of antimicrobial peptides in
comparison to oligo peptides is reviewed. Meanwhile, the existing problems and the future trends are also discussed.

Key words: antimicrobial peptide, quantitative structure-activity relationship, descriptor, amino acid, mathematical model

CLC Number: