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Lastest Progress in Research on Pyrroloquinoline Quinone

TANG Liang, ZHANG Ling, LI Linzi, WANG Yin*   

  1. Zhejiang Academy of Medical Sciences, Hangzhou 310013, China
  • Online:2015-10-15 Published:2015-10-20

Abstract:

Pyrroloquinoline quinine (PQQ) is a redox cofactor of bacterial dehydrogenase and an antioxidant. It can prevent
oxidative reaction in vivo and cell damage caused by reactive oxygen species from biological active substances in vitro,
to provide nutrients and vitamins for cell growth. PQQ is a biological control agent for plant fungal pathogens, which
can induce protein kinase to play a part in the development of mammalian cell differentiation. PQQ can improve the crop
productivity by increasing the utilization rate of insoluble phosphate, which has close correlation with redox recycling
function as an anti-neurodegenerative, anticancer and pharmacological agent.

Key words: pyrroloquinoline quinone, redox, neuron protection, signal transduction

CLC Number: