Abstract: A high performance liquid chromatography method was developed for determining the migration of bisphenol A from plastic food packaging materials into food simulants such as water, 4% acetic acid solution (weight fraction), 30% ethanol solution (volume fraction) and fat simulants (hexane, isooctane and olive oil). The results showed that bisphenol A could migrate to foods from packaging materials during the contact with foods, especially in alcohol simulants. The migration rate of bisphenol A from packaging materials to foods revealed a dramatic increase at the temperature of over 60 ℃. Under the condition of microwave heating, microwave power at 700 W could result in the fastest migration of bisphenol A. The detection limit of the method was 0.3 ng/mL with a linear range of 0.5－100 ng/mL and a linear correlation coefficient of 0.9997. The average recovery rate of the method was 92.0%－102.4% with a relative standard deviation (RSD) of less than 2.84%.

Key words: plastic food packaging material, stimulant, bisphenol A, migration, high performance liquid chromatography (HPLC)