Abstract: Landes geese were used as the materials to explore the expression rule of FAS mRNA in fatty liver through real-time fluorescence quantitative PCR method during overfeeding weeks. Fluorescence quantitative PCR results showed that the expression of FAS gene revealed an obvious increase during pre-feeding fold and pro-feeding 1 week, feeding 2 weeks, feeding 3 weeks and feeding 4 weeks, which were 0.035, 0.128, 0.253, 0.876 fold and 1.009 fold enhancement, respectively. A positive genetic correlation between FAS mRNA expression in fatty liver tissue and feeding weeks was observed. These results suggested that FAS gene had a certain readjustment function during the developing process of fatty liver in goose and the process of body fat deposition. Thus, FAS is a regulation gene to promote fat deposit inside liver of goose, which provides valuable technical parameters for future studies of fatty liver.

Key words: feeding, fatty liver of goose, fatty acid synthase, gene expression