Preparation and Antibacterial Activity of Water-soluble O-Carboxymethyl Chitosan Quaternary Ammonium Salt

doi:10.7506/spkx1002-6630-201109018

Abstract

Abstract: Objective: To prepare and structurally characterize water-soluble O-carboxymethyl chitosan quaternary ammonium salt (CMCQAS), and to evaluate its antibacterial activity. Method: The preparation of water-soluble CMCQAS was conducted by using 3-chloro-2-hydroxypropyl trimethyl ammonium chloride (CTA) and chloroacetic acid as grafting agents. Its structure was characterized by IR and ultraviolet spectroscopy and its antibacterial activitiy against S. aureus, E. coli and A. niger were evaluated. Results: The prepared water-soluble CMCQAS had a distinct antibacterial activity against S. aureus, E. coli and A.niger, which was higher than that of chitosan (CS).

Key words: chitosan, carboxymethyl, quaternary ammonium salt, antibacterial activity

CLC Number:

O627.181

LI Xiao-fang，FENG Xiao-qiang，YANG Sheng，MA Zhi-jun，XU Ben-jin. Preparation and Antibacterial Activity of Water-soluble O-Carboxymethyl Chitosan Quaternary Ammonium Salt[J]. FOOD SCIENCE, 2011, 32(9): 79-81.

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Preparation and Antibacterial Activity of Water-soluble O-Carboxymethyl Chitosan Quaternary Ammonium Salt

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