Uncertainty Evaluation for Nicotinamide Determination in Infant Formula Milk Powder by High Performance Liquid Chromatography

doi:10.7506/spkx1002-6630-201116072

FOOD SCIENCE ›› 2011, Vol. 32 ›› Issue (16): 330-333.doi: 10.7506/spkx1002-6630-201116072

• Analysis & Detection • Previous Articles Next Articles

Uncertainty Evaluation for Nicotinamide Determination in Infant Formula Milk Powder by High Performance Liquid Chromatography

HUO Yan-min，WANG Yan-li，WANG Jun，ZHOU Li-li，ZHU Jian-hua，ZHANG Hui，XUE Xia

(National Center for Quality Supervision and Inspection of Processed Food (Shandong), Shandong Supervision and Inspection Institute for Product Quality, Jinan 250103, China)

Received:2018-05-21 Revised:2018-05-21 Online:2011-08-25 Published:2011-07-26

Abstract

Abstract: A mathematical model was established to evaluate the uncertainty of determining nicotinamide in infant formula milk powder by high performance liquid chromatography with diode-array detection. According to the relevant regulations given in JJF 1135-2005 Evaluation of Uncertainty in Chemical Analysis Measurement and JJF 1059－1999 Evaluation and Expression of Uncertainty in Measurement, the sources of uncertainty for determining nicotinamide in infant formula milk powder were explored. Finally, the standard uncertainty and the expanded uncertainty were achieved. The content of nicotinamide in infant formula milk powder determined by HPLC was (63.01 ± 3.50) mg/kg. The major sources of uncertainty affecting determination results were pre-treatment, standard solution and standard curve fitting.

Key words: uncertainty, nicotinamide, infant formula milk powder, high performance liquid chromatography (HPLC)

CLC Number:

O657.72

HUO Yan-min，WANG Yan-li，WANG Jun，ZHOU Li-li，ZHU Jian-hua，ZHANG Hui，XUE Xia. Uncertainty Evaluation for Nicotinamide Determination in Infant Formula Milk Powder by High Performance Liquid Chromatography[J]. FOOD SCIENCE, 2011, 32(16): 330-333.

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Uncertainty Evaluation for Nicotinamide Determination in Infant Formula Milk Powder by High Performance Liquid Chromatography

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