Abstract: In order to provide a reference for relevant researchers and administrative decision makers, a bibliometric analysis of the papers published in Science Citation Index Expanded (SCI-E) database over the last 20 years was carried out to examine the current status and trends in global nutrigenomic research. The results showed that achievements in global nutrigenomic research present a fluctuating growth trend and are still in the “climbing” stage with tremendous and broad prospects for development. The United States as well as research institutions in the country has absolute advantages in the field of nutrigenomic research, but China has not yet entered into the list of major countries and institutions in the world. Nutrition and dietetics are the most important direction in nutrigenomics. Multidisciplinary and cross-disciplinary cooperative research is becoming mainstream. Research hotspots are shifting towards diet and health, from disease treatment to disease prevention (keeping healthy). Nutrigenomic applications, clinical medicine, emerging cross-disciplinary subjects, epigenome damage and mediterranean diet are frontiers of nutrigenomic research. As the most populous country in the world, China should attach more importance to the further development of nutrigenomics so as to meet people’s health demands and seize the commanding heights in the field of biomedicine and health.

Key words: nutrigenomics, bibliometrics, research situation, Science Citation Index, Web of Science