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Advances in the study of postbiotics to regulate obesity

  

  • Received:2022-09-08 Revised:2023-07-14 Online:2023-09-15 Published:2023-09-29

Abstract: Postbiotics are dead bacteria with no vital characteristics and their metabolic components. Since many substances in postbiotics are still biologically active, they are widely used in the prevention and treatment of various diseases because they are safer and more stable than probiotics. In recent years, many studies have shown that postbiotics have the effect of regulating lipid metabolism to improve obesity, which is expected to be a new strategy for the treatment of obesity. Based on this, this paper introduces the harmful effects of obesity and its possible causes of formation, illustrates the potential mechanisms of postbiotic regulation of diseases, reviews the research on the role of postbiotics in the process of obesity regulation from both postbiotic bacteria and postbiotic metabolites, and provides references for the next research on the application of postbiotics in obesity regulation.

Key words: obesity, postbiotic, metabolites

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