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Research Progress on the Correlation between Different Dietary Patterns and Hyperuricemia Mediated by Intestinal Flora

Han Lu 2,Shi-Jie WANG2   

  • Received:2023-03-16 Revised:2024-03-15 Online:2024-05-15 Published:2024-04-30
  • Contact: Shi-Jie WANG E-mail:mrshjwang@163.com

Abstract: Hyperuricemia (HUA) is a disorder of purine metabolism caused by the imbalance of uric acid production and excretion, which can lead to gout and renal function damage in severe cases. At present, the prevalence of HUA/gout in China is increasing and the HUA/gout patients are younger and younger. In recent years, studies have shown that the intestinal flora of patients with HUA/gout is imbalance compared with that of healthy people, and different dietary patterns will affect the level of uric acid by adjusting the intestinal flora. This paper elaborated on the characteristics of intestinal flora of patients with HUA/gout, the effects of intestinal flora on uric acid metabolism, which laid a theoretical foundation for prevention, early diagnosis and auxiliary treatment of HUA/gout. This paper also summarizedand the impact of different dietary patterns on uric acid level, which guided patients to effectively prevent and delay the occurrence of HUA/gout by adjusting their diet patterns.

Key words: Hyperuricemia, gout, intestinal flora, dietary patterns

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