Effect of Polysaccharide from Moso Bamboo Leaves on Blood Lipid of Mice with Hyperlipemia

doi:10.7506/spkx1002-6630-201009058

Abstract

Abstract:

In order to investigate the functions of polysaccharide from moso bamboo leaves (PMBL) for decreasing blood lipid and liver lipid and promoting the recovery of damaged liver, the mice model with hyperlipidemia was established through the feeding of high-fat food to evaluate the effect of PMBL on lipid metabolism of mice. Totally 50 mice were divided into 5 groups designated as hyperlipidemia model group, PMBL groups at low, middle and high dosages, and positive control group. Blood lipid, serum ALT, crude fat content in liver, liver index and morphological change of liver tissues were evaluated. Results indicated PMBL could result in a significant reduction of total cholesterol, triglyceride and low-density lipoprotein in serum; however, no significant effect on high-density lipoprotein was observed. In addition, PMBL could decrease crude fat content in liver, and improve the hepatic function of mice. In a word, PMBL exhibited anti-lipidemic activity and lipid-reducing effect in liver to enhance the repairing of damaged liver in mice with hyperlipidemia at the condition of optimal dosage.

Key words: polysaccharide from moso bamboo leaves, hyperlipemia, fatty liver, blood-lipid lowering, hepatic function

CLC Number:

Q71
O629.12

DING Hong-xiu1,2，GAO Yin-yu2,*，CHAO Hong-juan2，XIA Dong-hua2. Effect of Polysaccharide from Moso Bamboo Leaves on Blood Lipid of Mice with Hyperlipemia[J]. FOOD SCIENCE, 2010, 31(9): 259-262 https://doi.org/10.7506/spkx1002-6630-201009058

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Effect of Polysaccharide from Moso Bamboo Leaves on Blood Lipid of Mice with Hyperlipemia

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