关键词: 手性, 农药, 兽药, 免疫分析, 识别机制

Abstract:

The enantiomers of chiral drugs exhibit stereoselective differences in their metabolic transformation and toxicity
in living organisms. Therefore, there is a need for deeper research and analysis of chiral pesticides and veterinary drugs
in the form of enantiomers. Immunoassay has attracted increasing attention in the field of chiral pesticides and veterinary
drugs because of its fast operation, high specificity and excellent sensitivity. The recent applications of immunoassay in
the detection of chiral pesticides and veterinary drugs are summarized. Meanwhile, this paper presents a review of recent
advances in the application of antibody stereoselectivity, molecular simulation and quantitative structure-activity relationship
in the immune recognition mechanism. Moreover, future trends in the research and application of immunoassay in this field
are discussed.

Key words: chiral, pesticides, veterinary drugs, immunoassay, recognition mechanism