食品科学

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外源核苷酸与免疫功能研究进展

王 楠,蔡夏夏,李 勇*   

  1. 北京大学公共卫生学院营养与食品卫生学系,北京 100191
  • 出版日期:2016-03-15 发布日期:2016-03-17

Advances in Research on Exogenous Nucleotides and Immune Functions

WANG Nan, CAI Xiaxia, LI Yong*   

  1. Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing 100191, China
  • Online:2016-03-15 Published:2016-03-17

摘要:

核苷酸是一类生物小分子,参与了生物体几乎所有生化反应过程,其中对维持机体免疫功能,促进免疫细胞的增殖和细胞因子的分泌具有重要作用。由于免疫细胞更新迅速,内源性从头合成的核苷酸无法满足需求,因此外源性核苷酸,尤其是膳食核苷酸与机体免疫功能有密切联系。本文就外源核苷酸对机体免疫功能的影响进行综述。

关键词: 外源核苷酸, 免疫功能, 炎症

Abstract:

Nucleotides (NTs) are low-molecular-weight biological molecules crucial to biochemical processes. They play
an important role in maintaining the immune system, accelerating the proliferation of immune cells and the secretion of
cytokines. Although endogenous production serves as the major nucleotide source, evidence suggests that exogenous
sources, mainly dietary nucleotides, have more connection with immune system. This article reviews previous researches on
the effects of NTs on immune function.

Key words: exogenous nucleotides, immune function, inflammation

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