食品科学 ›› 2010, Vol. 31 ›› Issue (12): 21-24.doi: 10.7506/spkx1002-6630-201012005

• 工艺技术 • 上一篇    下一篇

VD3- 壳聚糖复合物的超临界二氧化碳注入法制备工艺

洪 流,沈佩琼,孙丽君,赵亚平*   

  1. 上海交通大学化学化工学院
  • 收稿日期:2009-07-24 修回日期:2009-12-27 出版日期:2010-06-15 发布日期:2010-12-29
  • 通讯作者: 赵亚平 E-mail:ypzhao@sjtu.edu.cn
  • 基金资助:

    国家“863”计划项目(2007AA10Z350)

Supercritical Carbon Dioxide Impregnation of Vitamin D3 into Chitosan Particles

HONG Liu,SHEN Pei-qiong,SUN Li-jun,ZHAO Ya-ping*   

  1. School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China
  • Received:2009-07-24 Revised:2009-12-27 Online:2010-06-15 Published:2010-12-29
  • Contact: ZHAO Ya-ping* E-mail:ypzhao@sjtu.edu.cn

摘要:

以壳聚糖粒子为载体,VD3 为模型物,采用超临界二氧化碳注入法制备VD3- 壳聚糖复合物。采用紫外测试法考察过程参数压力、温度以及时间对VD3 在VD3- 壳聚糖复合物中负载量的影响。结果表明:随着压力和温度的增加,VD3 负载量均为先增大后减小;当压力20MPa、温度35℃时,VD3 负载量达到最大值;当温度和压力一定时,时间由1h 增至3h,VD3 负载量也有不同程度的增加。

关键词: 超临界二氧化碳注入法, VD3- 壳聚糖复合物, 制备

Abstract:

The impregnation of vitamin D3 into chitosan particles using supercritical CO2 fluid was investigated with respect to the effects of pressure, temperature and length of impregnation time evaluated by UV-vis spectroscopy. The results showed that with increasing pressure, VD3 impregnation amount initially increased and then decreased; as temperature increased, an identical change pattern in VD3 impregnation amount was observed. VD3 impregnation amount reached its maximum value under the conditions of 20 MPa and 35 ℃. Increasing length of impregnation time from 1 to 3 h resulted in a higher VD3 impregnation amount when pressure and temperature kept unchangeable.

Key words: supercritical CO2 impregnation, vitamin D3, chitosan

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