Abstract:

In this paper, a glassy carbon electrode modified with gold nanoparticles and graphene was prepared. The surfacemodifying
materials were characterized, and the electrochemical behaviors of salbutamol on the modified electrode were
investigated by cyclic voltammetry. The detection range of salbutamol was employed by differential pulse voltammetry. The
immunosensor demonstrated excellent performance for salbutamol detection with a broad linear range of 1 × 10-6 to 5 × 10-3g/L
and a limit of detection of 2 × 10-7g/L. A good recovery of salbutamol in the range of 91.2%–102.2% was obtained in pork,
beef, duck and pork liver. This modified electrode revealed excellent reproducibility and stability.

Key words: salbutamol, nanogold, graphene, nanoparticle immunosensor